The Clinical Pharmacology of Anti-Inflammatory Agents
نویسندگان
چکیده
منابع مشابه
Clinical pharmacology of nonsteroidal anti-inflammatory drugs in dogs.
OBJECTIVES To discuss the clinical pharmacology of currently licensed veterinary NSAIDs and to review gastrointestinal and renal adverse effects as well as drug-drug interactions that have been reported with these drugs. To review the use of NSAIDs in the peri-operative setting and their use in patients with osteoarthritis. To further review the reported effects of NSAIDs on canine articular ca...
متن کاملNew anti-inflammatory agents.
The pyrrole derivatives la, b and 2a, b were used as precursors for the preparation of N-substituted pyrrole derivatives 3a, b-9a, b and pyrrolo[2,3-d]pyrimidines 13-16. Also, all the newly prepared products were tested for anti-inflammatory activity as analogues to fenamates, and some of them revealed moderate anti-inflammatory activity compared to the standard drug indomethacin.
متن کاملA Comparative Study upon the Therapeutic Indices of Some Natural and Synthetic Anti-inflammatory Agents
Objective(s) The aim of the present study was to compare the therapeutic indices of several agents used in treatment of inflammatory conditions which included: Vitamin E, hydro-alcoholic extracts of Glycyrrhiza glabra, Matricaria aurea, dexamethasone, piroxicam and diclofenac using Wehi-164 fibrosarcoma cells. Materials and Methods Cytotoxicity evaluation was based on vital dye exclusion ass...
متن کاملClinical pharmacology of neuromuscular blocking agents.
The clinical pharmacology of neuromuscular blocking agents is described. During neuromuscular blockade, succinylcholine attaches to receptors in the motor end plate and depolarizes the neuromuscular junction, making the end plate refractory to acetylcholine. The nondepolarizing relaxants have a structure similar to that of succinylcholine and bind to the same receptors. Instead of depolarizing ...
متن کاملAnti-inflammatory and Analgesic Agents
Inflammatory diseases including arthritis and rheumatism are major group of prevalent diseases. Most of the available non-steroidal anti-inflammatory drugs are effective in inflammatory conditions of the joints, but are devoid of gastro protective property. Many substances, interfering with the inflammatory response have been isolated from Indian medicinal plants (IMP). The review analyses form...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1987
ISSN: 0003-4967
DOI: 10.1136/ard.46.7.567-b